TB-Profiler result

Run: ERR2653007
Summary

Run ID: ERR2653007

Sample name:

Date: 31-03-2023 22:26:31

Number of reads: 1083371

Percentage reads mapped: 99.29

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7594 p.Arg98His missense_variant 0.11
mshA 575871 p.His175Arg missense_variant 0.11
ccsA 620176 p.Val96Leu missense_variant 0.17
rpoC 766218 p.Asp950Gly missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777781 p.Thr234Ala missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102273 p.Ile257Thr missense_variant 0.1
PPE35 2170060 p.Val185Leu missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065463 c.729T>C synonymous_variant 0.11
ald 3087622 p.Ala268Val missense_variant 0.11
fbiD 3339741 c.624G>T synonymous_variant 0.19
fbiD 3339744 c.627A>C synonymous_variant 0.18
fbiD 3339753 c.636A>G synonymous_variant 0.19
fbiB 3642219 p.Ala229Ser missense_variant 0.11
rpoA 3878630 c.-123G>C upstream_gene_variant 0.14
embC 4239925 p.Asp21Glu missense_variant 0.11
embC 4240660 c.798C>A synonymous_variant 0.11
embA 4242491 c.-742C>A upstream_gene_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0