TB-Profiler result

Run: ERR2653025
Summary

Run ID: ERR2653025

Sample name:

Date: 31-03-2023 22:27:20

Number of reads: 1274672

Percentage reads mapped: 99.65

Strain: lineage4.9

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 762230 c.2424G>A synonymous_variant 0.11
embR 1416792 c.555delG frameshift_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102973 p.Phe24Leu missense_variant 0.15
katG 2154745 p.Ala456Asp missense_variant 0.11
Rv1979c 2222036 c.1129C>T synonymous_variant 1.0
fprA 3475314 c.1308G>A synonymous_variant 0.12
fbiB 3642838 p.Leu435Ser missense_variant 0.12
fbiB 3642843 p.Asp437Asn missense_variant 0.12
rpoA 3878630 c.-123G>C upstream_gene_variant 0.12
embA 4242460 c.-773G>A upstream_gene_variant 0.12
ubiA 4269915 c.-82T>C upstream_gene_variant 0.11
whiB6 4338391 p.Thr44Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0