TB-Profiler result

Run: ERR270635

Summary

Run ID: ERR270635

Sample name:

Date: 31-03-2023 23:06:10

Number of reads: 4109207

Percentage reads mapped: 99.63

Strain: lineage4.7

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
ethA 4326337 c.1136delA frameshift_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6608 p.Val457Ile missense_variant 0.99
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576741 p.Ala465Gly missense_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 0.99
inhA 1674952 p.Pro251Ala missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155467 p.Asp215Glu missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.24
thyA 3073806 c.666C>G synonymous_variant 0.19
clpC1 4038857 c.1848C>A synonymous_variant 0.22
embC 4239842 c.-21C>A upstream_gene_variant 0.31
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0