TB-Profiler result

Run: ERR2747661
Summary

Run ID: ERR2747661

Sample name:

Date: 31-03-2023 23:29:02

Number of reads: 45427

Percentage reads mapped: 15.47

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.97
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
eis 2715125 p.Thr70Ala missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474394 p.Gly130Cys missense_variant 0.4
fprA 3474427 p.Val141Ile missense_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0