TB-Profiler result

Run: ERR279587
Summary

Run ID: ERR279587

Sample name:

Date: 31-03-2023 23:41:58

Number of reads: 201231

Percentage reads mapped: 96.76

Strain: lineage4.9;lineage2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.08
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9005 c.1704G>T synonymous_variant 0.5
ccsA 620625 p.Ile245Met missense_variant 1.0
ccsA 620660 p.Arg257His missense_variant 1.0
mmpL5 775853 c.2627_2628insT frameshift_variant 0.67
Rv1258c 1406228 c.1113C>T synonymous_variant 1.0
rrs 1471713 n.-133G>T upstream_gene_variant 1.0
rrs 1471758 n.-88G>T upstream_gene_variant 0.5
rrs 1471873 n.28C>A non_coding_transcript_exon_variant 0.67
rrs 1473208 n.1365_1366delTG non_coding_transcript_exon_variant 0.67
rrl 1473392 n.-266C>A upstream_gene_variant 0.67
rrl 1474290 n.633T>C non_coding_transcript_exon_variant 1.0
inhA 1673816 c.-386G>A upstream_gene_variant 0.67
fabG1 1674152 p.Pro238Gln missense_variant 0.5
ndh 2103116 c.-74C>A upstream_gene_variant 0.67
PPE35 2169997 p.Ser206Cys missense_variant 0.5
PPE35 2170561 p.Gly18Arg missense_variant 0.4
Rv1979c 2221812 c.1353G>A synonymous_variant 1.0
Rv1979c 2223220 c.-56G>A upstream_gene_variant 1.0
kasA 2518589 p.Gly159Arg missense_variant 0.67
eis 2715122 p.Val71Met missense_variant 0.4
thyX 3067909 p.Ala13Thr missense_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339303 c.186C>T synonymous_variant 1.0
fprA 3475152 p.Leu382Phe missense_variant 0.67
rpoA 3877963 p.Arg182Pro missense_variant 1.0
rpoA 3878132 p.Ala126Thr missense_variant 1.0
embC 4240088 p.Gly76Arg missense_variant 1.0
embA 4243460 c.228C>T synonymous_variant 0.75
embA 4245881 p.Asp883Glu missense_variant 1.0
embB 4248481 p.Phe656Leu missense_variant 0.5
aftB 4268589 p.Ala83Val missense_variant 0.4
ethA 4326424 c.1050T>G synonymous_variant 1.0
ethA 4326633 p.His281Tyr missense_variant 0.5
ethA 4328291 c.-818C>T upstream_gene_variant 0.67
ethA 4328303 c.-831delA upstream_gene_variant 0.67
gid 4407588 c.615A>G synonymous_variant 1.0