TB-Profiler result

Run: ERR2843479
Summary

Run ID: ERR2843479

Sample name:

Date: 31-03-2023 23:50:31

Number of reads: 974725

Percentage reads mapped: 99.25

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.98
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 8534 c.1233G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoB 759914 c.108T>C synonymous_variant 0.11
rpoC 763966 c.597C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303819 p.Ala297Ser missense_variant 0.12
embR 1417276 c.72C>T synonymous_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472365 n.520G>A non_coding_transcript_exon_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169071 c.1542A>T synonymous_variant 0.24
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987021 c.183G>T synonymous_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3640818 c.-717G>C upstream_gene_variant 0.1
fbiA 3640819 p.Val93Leu missense_variant 0.1
rpoA 3878067 c.441C>A synonymous_variant 0.14
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246122 c.-392C>T upstream_gene_variant 0.14
embB 4249528 c.3015C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0