TB-Profiler result

Run: ERR3275382
Summary

Run ID: ERR3275382

Sample name:

Date: 11-08-2022 16:39:06

Number of reads: 3278974

Percentage reads mapped: 99.98

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6358 c.-944C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491160 p.Lys126Asn missense_variant 0.13
fgd1 491161 p.Glu127* stop_gained 0.14
fgd1 491493 c.711C>A synonymous_variant 0.2
rpoC 765588 p.Pro740Gln missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.12
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.12
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.12
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.11
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.11
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.3
PPE35 2170053 p.Thr187Ser missense_variant 0.3
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3474888 c.882G>T synonymous_variant 0.12
clpC1 4039643 c.1062C>T synonymous_variant 1.0
embC 4239767 c.-96G>A upstream_gene_variant 0.93
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245690 p.Gly820Trp missense_variant 0.13
embB 4246544 p.Thr11Pro missense_variant 0.37
embB 4246548 p.Pro12Gln missense_variant 0.29
embB 4246555 c.42G>C synonymous_variant 0.28
embB 4246556 p.Ala15Pro missense_variant 0.28
embB 4246563 p.Leu17Trp missense_variant 0.24
embB 4246567 c.54G>T synonymous_variant 0.22
embB 4249222 c.2709C>A synonymous_variant 0.14
embB 4249732 c.3219C>G synonymous_variant 1.0
ethA 4326426 p.Gly350Cys missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0