TB-Profiler result

Run: ERR3439282

Summary

Run ID: ERR3439282

Sample name:

Date: 01-04-2023 02:01:15

Number of reads: 49999

Percentage reads mapped: 3.33

Strain: lineage4.9

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1.8.1 M.bovis None None 0.08
lineage4 Euro-American LAM;T;S;X;H None 0.93
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 767098 c.3729T>C synonymous_variant 0.5
rpoC 767119 c.3750A>G synonymous_variant 0.4
rpoC 767134 c.3765C>A synonymous_variant 0.4
rpoC 767152 c.3783T>G synonymous_variant 0.67
rpoC 767155 c.3786C>G synonymous_variant 0.67
rpoC 767167 c.3798C>T synonymous_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
rrs 1472100 n.255T>C non_coding_transcript_exon_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67
rrs 1472181 n.336G>A non_coding_transcript_exon_variant 0.67
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.67
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.75
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.75
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.67
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 1.0
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 1.0
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 1.0
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 1.0
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.33
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.67
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.43
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.71
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.5
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.33
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.89
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.22
rrl 1476381 n.2724G>A non_coding_transcript_exon_variant 0.5
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.89
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.71
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.38
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.67
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.78
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.43
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.22
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.33
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.38
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.33
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.29
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.8
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.4
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
PPE35 2169611 c.1002C>T synonymous_variant 1.0
Rv2752c 3065988 p.Glu68Asp missense_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4242642 p.Arg927His missense_variant 0.5
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0