TB-Profiler result

Run: ERR3797010
Summary

Run ID: ERR3797010

Sample name:

Date: 01-04-2023 03:02:07

Number of reads: 14408

Percentage reads mapped: 23.34

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 575821 c.474G>C synonymous_variant 1.0
mshA 575824 c.477T>A synonymous_variant 1.0
mshA 575842 c.495G>C synonymous_variant 1.0
mshA 575864 c.517T>C synonymous_variant 1.0
mshA 575875 c.528C>G synonymous_variant 1.0
mshA 575878 c.531A>G synonymous_variant 1.0
mshA 575887 c.540G>C synonymous_variant 1.0
mshA 575896 c.549G>C synonymous_variant 1.0
mshA 575908 c.561A>G synonymous_variant 1.0
mshA 575920 c.573C>G synonymous_variant 1.0
mshA 575944 c.597T>C synonymous_variant 1.0
mshA 575950 c.603C>G synonymous_variant 1.0
rpoB 760475 c.669A>G synonymous_variant 1.0
rpoB 760481 c.675G>C synonymous_variant 1.0
rpoB 760484 c.678A>G synonymous_variant 1.0
rpoB 760514 c.708C>T synonymous_variant 1.0
rpoB 760522 p.Ser239Asn missense_variant 1.0
rpoB 760528 p.Gln241Arg missense_variant 1.0
rpoB 760532 c.726T>C synonymous_variant 1.0
rpoB 760533 p.Val243Thr missense_variant 1.0
rpoB 760547 c.741G>C synonymous_variant 1.0
rpoB 761999 c.2193G>C synonymous_variant 1.0
rpoB 762002 c.2196C>G synonymous_variant 1.0
rpoB 762053 c.2247T>C synonymous_variant 1.0
rpoB 762065 c.2259T>C synonymous_variant 1.0
rpoB 762317 c.2511A>G synonymous_variant 1.0
rpoB 762338 c.2532T>C synonymous_variant 1.0
rpoB 762347 c.2541T>C synonymous_variant 1.0
rpoB 762362 p.Glu852Asp missense_variant 1.0
rpoB 762369 c.2563T>C synonymous_variant 1.0
rpoC 762380 c.-990T>G upstream_gene_variant 1.0
rpoC 762395 c.-975G>C upstream_gene_variant 1.0
rpoC 762398 c.-972T>C upstream_gene_variant 1.0
rpoC 762401 c.-969G>C upstream_gene_variant 1.0
rpoC 762404 c.-966T>C upstream_gene_variant 1.0
rpoC 762410 c.-960T>C upstream_gene_variant 1.0
rpoC 762416 c.-954A>G upstream_gene_variant 1.0
rpoC 763546 c.177A>G synonymous_variant 1.0
rpoC 763570 c.201G>C synonymous_variant 1.0
rpoC 763573 c.204G>C synonymous_variant 1.0
rpoC 763594 c.225C>T synonymous_variant 1.0
rpoC 763636 c.267T>C synonymous_variant 1.0
rpoC 766627 c.3258G>C synonymous_variant 1.0
rpoC 766630 c.3261G>C synonymous_variant 1.0
rpoC 766645 c.3276A>G synonymous_variant 1.0
rpoC 766651 c.3282T>C synonymous_variant 1.0
rpoC 766657 c.3288A>G synonymous_variant 1.0
rpoC 766658 p.Arg1097Gly missense_variant 1.0
rpoC 766666 c.3297C>G synonymous_variant 1.0
rpoC 766672 c.3303T>C synonymous_variant 1.0
fbiC 1303509 c.579G>C synonymous_variant 1.0
fbiC 1303512 c.582T>C synonymous_variant 1.0
fbiC 1303545 c.615A>G synonymous_variant 1.0
fbiC 1303575 c.645G>C synonymous_variant 1.0
fbiC 1303584 c.654C>G synonymous_variant 1.0
fbiC 1303590 c.660A>G synonymous_variant 1.0
fbiC 1303602 c.672A>G synonymous_variant 1.0
fbiC 1303605 c.675C>G synonymous_variant 1.0
fbiC 1303608 c.678G>A synonymous_variant 1.0
inhA 1674654 c.453G>C synonymous_variant 1.0
inhA 1674660 c.459G>T synonymous_variant 1.0
inhA 1674663 c.462G>C synonymous_variant 1.0
inhA 1674703 c.502T>C synonymous_variant 0.67
inhA 1674714 c.513C>G synonymous_variant 0.67
inhA 1674718 c.517A>C synonymous_variant 0.67
inhA 1674726 c.525G>A synonymous_variant 0.67
inhA 1674729 c.528G>C synonymous_variant 0.67
inhA 1674750 c.549T>C synonymous_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518146 p.Phe11Tyr missense_variant 1.0
kasA 2518156 c.42T>C synonymous_variant 1.0
kasA 2518162 c.48G>A synonymous_variant 1.0
kasA 2518172 p.Thr20Ala missense_variant 1.0
kasA 2518190 p.Ser26Ala missense_variant 1.0
kasA 2518195 c.81G>A synonymous_variant 1.0
kasA 2518220 c.106C>T synonymous_variant 1.0
kasA 2518226 p.Ala38Ser missense_variant 1.0
kasA 2518245 p.His44Arg missense_variant 1.0
kasA 2518248 p.Ala45Val missense_variant 1.0
clpC1 4038368 c.2337T>C synonymous_variant 1.0
clpC1 4038388 c.2317T>C synonymous_variant 1.0
clpC1 4038395 c.2310C>T synonymous_variant 1.0
clpC1 4038398 c.2307G>C synonymous_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4038433 c.2272C>T synonymous_variant 0.75
clpC1 4038444 p.Ala754Lys missense_variant 0.75
clpC1 4038446 c.2259T>C synonymous_variant 0.75
clpC1 4038456 p.Val750Glu missense_variant 0.75
clpC1 4038460 p.Leu749Met missense_variant 0.75
clpC1 4038494 c.2211G>C synonymous_variant 0.75
clpC1 4038499 p.Ser736Gly missense_variant 0.75
clpC1 4038956 c.1749T>C synonymous_variant 1.0
clpC1 4038965 c.1740T>C synonymous_variant 1.0
clpC1 4038971 c.1734T>C synonymous_variant 1.0
clpC1 4038974 c.1731T>C synonymous_variant 1.0
clpC1 4038989 c.1716T>C synonymous_variant 1.0
clpC1 4038997 c.1708T>C synonymous_variant 1.0
clpC1 4039022 c.1683A>G synonymous_variant 1.0
clpC1 4039031 c.1674T>G synonymous_variant 1.0
clpC1 4039037 c.1668T>C synonymous_variant 1.0
clpC1 4039046 c.1659C>T synonymous_variant 1.0
clpC1 4039085 c.1620A>G synonymous_variant 1.0
clpC1 4039097 c.1608G>C synonymous_variant 1.0
clpC1 4039391 c.1314T>C synonymous_variant 1.0
clpC1 4039556 c.1149G>C synonymous_variant 0.67
clpC1 4039574 p.Ala377Ser missense_variant 0.67
clpC1 4039610 c.1095G>C synonymous_variant 1.0
clpC1 4039616 c.1089G>C synonymous_variant 1.0
embB 4248316 c.1803C>G synonymous_variant 1.0
embB 4248319 c.1806A>G synonymous_variant 1.0
embB 4248322 c.1809G>T synonymous_variant 1.0
embB 4248343 c.1830G>C synonymous_variant 1.0
embB 4248349 c.1836G>C synonymous_variant 1.0
embB 4248350 c.1837T>C synonymous_variant 1.0
embB 4248355 c.1842A>C synonymous_variant 1.0
embB 4248358 c.1845C>G synonymous_variant 1.0
embB 4248361 c.1848A>G synonymous_variant 1.0
embB 4248362 p.Ser617Lys missense_variant 1.0
embB 4248382 c.1869C>T synonymous_variant 0.67
gid 4407588 c.615A>G synonymous_variant 1.0