TB-Profiler result

Run: ERR3838819
Summary

Run ID: ERR3838819

Sample name:

Date: 01-04-2023 03:28:28

Number of reads: 1025095

Percentage reads mapped: 99.65

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575761 c.414C>T synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.18
rpoB 759814 p.Asp3Gly missense_variant 1.0
rpoC 767153 c.3786delC frameshift_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781502 c.-58G>T upstream_gene_variant 1.0
fbiC 1304042 p.Trp371Leu missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474954 n.1297A>G non_coding_transcript_exon_variant 0.11
fabG1 1673600 p.Gly54Ala missense_variant 1.0
rpsA 1834568 p.Asp343His missense_variant 0.12
tlyA 1917755 c.-185A>G upstream_gene_variant 0.12
tlyA 1917822 c.-118G>T upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102254 c.789C>T synonymous_variant 0.12
katG 2155272 c.840G>T synonymous_variant 0.11
PPE35 2170048 p.Leu189Val missense_variant 0.3
PPE35 2170053 p.Thr187Ser missense_variant 0.3
PPE35 2170109 p.Phe168Leu missense_variant 0.18
Rv1979c 2222937 c.228T>C synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289886 c.-645C>T upstream_gene_variant 0.18
kasA 2519083 c.969C>T synonymous_variant 0.12
thyX 3067353 p.Met198Thr missense_variant 0.12
fbiD 3339734 p.Ala206Gly missense_variant 0.67
Rv3083 3449155 p.Phe218Leu missense_variant 0.18
fprA 3474986 p.Val327Gly missense_variant 0.25
Rv3236c 3612533 p.Ala195Val missense_variant 0.13
fbiA 3640524 c.-19G>A upstream_gene_variant 0.11
fbiB 3642214 p.Ser227Leu missense_variant 0.12
embA 4245424 p.Ser731Phe missense_variant 0.18
embB 4247033 p.Ser174Arg missense_variant 0.3
aftB 4267951 p.Pro296Ser missense_variant 0.11
aftB 4268813 c.24G>T synonymous_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0