TB-Profiler result

Run: ERR4028192
Summary

Run ID: ERR4028192

Sample name:

Date: 01-04-2023 04:20:16

Number of reads: 1128197

Percentage reads mapped: 99.88

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 764498 p.Ser377Thr missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2169902 p.Leu237Phe missense_variant 0.19
PPE35 2169910 p.Asn235Tyr missense_variant 0.16
PPE35 2170048 p.Leu189Val missense_variant 0.22
PPE35 2170053 p.Thr187Ser missense_variant 0.25
PPE35 2170504 p.Glu37* stop_gained 0.11
kasA 2518470 p.Ala119Asp missense_variant 0.12
pepQ 2859324 c.1095C>T synonymous_variant 0.11
fprA 3475073 p.Val356Asp missense_variant 0.17
clpC1 4039508 c.1197G>C synonymous_variant 0.12
embC 4241397 p.Trp512Ser missense_variant 0.12
embA 4245188 c.1956G>T synonymous_variant 0.12
embB 4249672 c.3159G>T synonymous_variant 0.13