TB-Profiler result

Run: ERR4407553
Summary

Run ID: ERR4407553

Sample name:

Date: 01-04-2023 05:50:01

Number of reads: 4024801

Percentage reads mapped: 99.38

Strain: lineage4.6.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.12
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.11
rrs 1472584 n.739A>C non_coding_transcript_exon_variant 0.11
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.12
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.11
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.1
rrl 1474314 n.657G>T non_coding_transcript_exon_variant 0.12
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.17
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.2
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.2
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.25
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.25
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.2
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.12
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.12
rrl 1474799 n.1143delT non_coding_transcript_exon_variant 0.12
rrl 1474803 n.1146_1147insA non_coding_transcript_exon_variant 0.14
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.14
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.14
rrl 1474839 n.1186_1188dupAGG non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448567 p.His22Asp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878494 p.Gln5Arg missense_variant 1.0
rpoA 3878627 c.-120T>G upstream_gene_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 1.0
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0