TB-Profiler result

Run: ERR4769406
Summary

Run ID: ERR4769406

Sample name:

Date: 01-04-2023 06:39:16

Number of reads: 55085

Percentage reads mapped: 3.91

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.96
lineage4.9 Euro-American (H37Rv-like) T1 None 0.92
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.75
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.75
rrs 1472443 n.598A>T non_coding_transcript_exon_variant 0.5
rrs 1472446 n.601T>G non_coding_transcript_exon_variant 0.67
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.75
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.75
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 1.0
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0
rrs 1472466 n.621C>A non_coding_transcript_exon_variant 0.67
rrs 1472467 n.622G>C non_coding_transcript_exon_variant 1.0
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.4
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.4
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.75
rrs 1472599 n.754G>A non_coding_transcript_exon_variant 0.67
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.5
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.6
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.6
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.33
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.4
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.4
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.5
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.5
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.33
rrs 1473134 n.1289T>G non_coding_transcript_exon_variant 0.33
rrs 1473135 n.1290C>T non_coding_transcript_exon_variant 0.33
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.5
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.5
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.33
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.4
rrs 1473282 n.1437C>T non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.5
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.5
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.5
rrl 1473814 n.157A>G non_coding_transcript_exon_variant 0.5
rrl 1473815 n.158T>C non_coding_transcript_exon_variant 0.5
rrl 1473830 n.173T>C non_coding_transcript_exon_variant 0.67
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.67
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 0.67
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.67
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.75
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.75
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.67
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 1.0
rrl 1474414 n.757C>T non_coding_transcript_exon_variant 1.0
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 1.0
rrl 1474450 n.793T>C non_coding_transcript_exon_variant 1.0
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.75
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.6
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.5
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.67
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.5
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.67
rrl 1475761 n.2104C>T non_coding_transcript_exon_variant 0.67
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.67
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.67
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.67
rrl 1475767 n.2110G>A non_coding_transcript_exon_variant 0.67
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.67
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.5
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.62
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.57
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.5
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.43
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.43
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.6
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.75
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.8
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.75
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.75
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.75
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.75
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.5
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.5
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.75
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 1.0
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 1.0
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.5
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.6
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.6
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.75
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2156465 c.-354C>T upstream_gene_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0