TB-Profiler result

Run: ERR4769542
Summary

Run ID: ERR4769542

Sample name:

Date: 01-04-2023 06:44:02

Number of reads: 32022

Percentage reads mapped: 1.58

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
rpoB 762832 p.Ser1009Thr missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.33
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.4
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.4
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.4
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.4
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.33
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.67
rrl 1476728 n.3071T>C non_coding_transcript_exon_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0