TB-Profiler result

Run: ERR4811982
Summary

Run ID: ERR4811982

Sample name:

Date: 01-04-2023 11:47:15

Number of reads: 147625

Percentage reads mapped: 98.41

Strain: lineage4.1.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575222 c.-126C>A upstream_gene_variant 0.33
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775634 c.2847G>T synonymous_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102838 p.Ala69Thr missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289307 c.-66T>G upstream_gene_variant 0.4
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
pepQ 2859373 p.Pro349Leu missense_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3841222 p.Ala67Ser missense_variant 0.2
clpC1 4039337 c.1368A>G synonymous_variant 0.25
embC 4242613 p.Phe917Leu missense_variant 1.0
embC 4243065 p.Pro1068His missense_variant 0.4
embA 4245238 p.Asp669Gly missense_variant 0.33
embB 4247028 p.Leu172Arg missense_variant 0.67
ethA 4326996 p.Pro160Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0