TB-Profiler result

Run: ERR4812083

Summary

Run ID: ERR4812083

Sample name:

Date: 01-04-2023 11:50:59

Number of reads: 144858

Percentage reads mapped: 99.23

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7121 p.Pro628Thr missense_variant 0.22
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765928 c.2559C>A synonymous_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778941 c.-36A>G upstream_gene_variant 0.5
Rv1258c 1407180 p.Pro54Gln missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473977 n.320G>T non_coding_transcript_exon_variant 1.0
inhA 1673736 c.-466G>T upstream_gene_variant 0.67
ndh 2102840 p.Ile68Ser missense_variant 0.29
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518016 c.-99A>C upstream_gene_variant 0.29
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
folC 2747249 p.Pro117Gln missense_variant 0.4
Rv2752c 3065514 c.678C>A synonymous_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3474350 p.Pro115His missense_variant 0.33
Rv3236c 3613000 c.117G>T synonymous_variant 0.33
embC 4241133 p.Pro424Leu missense_variant 0.5
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249715 p.Asp1068Tyr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0