TB-Profiler result

Run: ERR4812287

Summary

Run ID: ERR4812287

Sample name:

Date: 01-04-2023 11:58:44

Number of reads: 148162

Percentage reads mapped: 99.52

Strain: lineage4

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9321 p.Val674Phe missense_variant 0.4
rpoB 759927 p.Pro41Thr missense_variant 0.33
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 761281 p.Gly492Val missense_variant 0.33
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305329 p.Leu800Pro missense_variant 0.29
fabG1 1674118 p.Glu227* stop_gained 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169423 p.Ser397Trp missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715247 p.Gly29Val missense_variant 0.18
ribD 2987414 c.576C>T synonymous_variant 0.67
Rv2752c 3065638 p.Leu185Arg missense_variant 0.5
thyA 3073884 c.588C>A synonymous_variant 0.29
ald 3086734 c.-86G>A upstream_gene_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087843 p.Gly342Arg missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640462 c.-81G>A upstream_gene_variant 1.0
fbiB 3642321 p.Val263Phe missense_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0