TB-Profiler result

Run: ERR4812627
Summary

Run ID: ERR4812627

Sample name:

Date: 01-04-2023 12:12:14

Number of reads: 131437

Percentage reads mapped: 98.86

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491366 p.Thr195Lys missense_variant 0.67
mshA 575679 p.Asn111Ser missense_variant 1.0
mshA 576114 p.Arg256Pro missense_variant 0.67
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 764726 p.Lys453Glu missense_variant 0.4
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpR5 779107 p.Leu40Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800673 c.-136G>T upstream_gene_variant 0.17
rplC 800743 c.-66C>A upstream_gene_variant 0.12
embR 1416517 c.831C>A synonymous_variant 0.22
embR 1416619 c.729C>A synonymous_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473684 n.27G>T non_coding_transcript_exon_variant 0.33
rrl 1474116 n.459G>T non_coding_transcript_exon_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168671 p.Gly648Ser missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288758 p.Gly162Cys missense_variant 0.5
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518165 c.51C>A synonymous_variant 0.33
Rv2752c 3065323 p.Ala290Asp missense_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038885 p.Gly607Asp missense_variant 0.2
panD 4044417 c.-136C>T upstream_gene_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4246410 p.Tyr1060His missense_variant 0.18
embB 4246584 p.Arg24Pro missense_variant 0.5
embB 4248477 p.Pro655Gln missense_variant 0.4
aftB 4267207 p.Val544Met missense_variant 1.0
ethR 4327892 p.Gly115Glu missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0