TB-Profiler result

Run: ERR4812934
Summary

Run ID: ERR4812934

Sample name:

Date: 01-04-2023 12:25:47

Number of reads: 94239

Percentage reads mapped: 98.06

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 0.5
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576114 p.Arg256Pro missense_variant 0.5
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 779319 c.-839T>C upstream_gene_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416546 p.Thr268Pro missense_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860147 p.Gly91Asp missense_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3236c 3612070 c.1047G>T synonymous_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245125 c.1893G>T synonymous_variant 0.67
embA 4245130 p.Pro633Gln missense_variant 0.5
embB 4247028 p.Leu172Arg missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407973 p.Val77Gly missense_variant 0.5