TB-Profiler result

Run: ERR4813222

Summary

Run ID: ERR4813222

Sample name:

Date: 01-04-2023 12:36:44

Number of reads: 178486

Percentage reads mapped: 99.41

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576458 p.Ala371Thr missense_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781596 c.37C>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102103 p.Tyr314Asp missense_variant 0.67
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746510 c.1089A>G synonymous_variant 0.75
folC 2747580 p.Gly7Cys missense_variant 0.25
folC 2747793 c.-195C>A upstream_gene_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.5
fbiB 3642050 c.516G>A synonymous_variant 0.5
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3878609 c.-102T>A upstream_gene_variant 0.5
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 0.4