TB-Profiler result

Run: ERR4813516
Summary

Run ID: ERR4813516

Sample name:

Date: 01-04-2023 12:48:39

Number of reads: 4823381

Percentage reads mapped: 99.22

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575631 p.Ser95Leu missense_variant 0.11
mshA 576108 p.Ala254Gly missense_variant 0.26
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778042 p.Ala147Thr missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407531 c.-191C>A upstream_gene_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917943 p.Ala2Ser missense_variant 0.12
PPE35 2168298 p.Pro772Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518992 p.Arg293His missense_variant 0.22
folC 2746544 p.Ala352Asp missense_variant 0.13
Rv2752c 3067058 c.-867T>C upstream_gene_variant 0.15
Rv2752c 3067103 c.-912G>A upstream_gene_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878559 c.-52G>C upstream_gene_variant 0.13
clpC1 4040192 c.513C>T synonymous_variant 0.11
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246552 p.Asn13Lys missense_variant 0.19
embB 4247028 p.Leu172Arg missense_variant 0.44
embB 4247033 p.Ser174Arg missense_variant 0.43
embB 4249408 c.2895G>A synonymous_variant 0.98
aftB 4268432 c.405C>A synonymous_variant 0.14