TB-Profiler result

Run: ERR4814705
Summary

Run ID: ERR4814705

Sample name:

Date: 01-04-2023 13:26:43

Number of reads: 270385

Percentage reads mapped: 97.23

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8973 p.Phe558Leu missense_variant 0.33
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 619923 c.33C>T synonymous_variant 0.4
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776404 p.Pro693Ser missense_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303603 p.Thr225Ala missense_variant 0.29
embR 1416543 p.Thr269Pro missense_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.67
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.67
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.67
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.67
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.67
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.67
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.67
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.67
rrl 1474641 n.984G>A non_coding_transcript_exon_variant 0.67
rpsA 1833564 p.Ser8* stop_gained 0.5
rpsA 1834386 p.Asp282Gly missense_variant 0.67
ndh 2102840 p.Ile68Asn missense_variant 0.15
katG 2154964 p.Ser383* stop_gained 0.33
PPE35 2168289 p.Thr775Asn missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519090 p.Ile326Val missense_variant 0.4
pepQ 2859378 c.1041G>T synonymous_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449101 p.Asn200Asp missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3841615 c.-195T>C upstream_gene_variant 0.25
embC 4240238 p.Ala126Ser missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ubiA 4269056 p.Leu260Met missense_variant 0.67
ethA 4326103 c.1371G>T synonymous_variant 0.33
ethR 4328185 p.Gly213Ser missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0