Run ID: ERR4814761
Sample name:
Date: 20-10-2023 07:38:18
Number of reads: 3504874
Percentage reads mapped: 95.57
Strain: lineage4.8
Drug-resistance: Other
Drug | Resistance | Supporting mutations |
---|---|---|
Rifampicin | ||
Isoniazid | ||
Ethambutol | ||
Pyrazinamide | ||
Streptomycin | R | rrs n.888G>A (0.80) |
Fluoroquinolones | ||
Moxifloxacin | ||
Ofloxacin | ||
Levofloxacin | ||
Ciprofloxacin | ||
Aminoglycosides | ||
Amikacin | ||
Capreomycin | ||
Kanamycin | ||
Cycloserine | ||
Ethionamide | ||
Clofazimine | ||
Para-aminosalicylic_acid | ||
Delamanid | ||
Bedaquiline | ||
Linezolid |
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | T1;T2;T3;T5 | RD219 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.8 | streptomycin |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
rpoC | 765369 | p.Thr667Met | missense_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.29 |
rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.38 |
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.92 |
rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.91 |
rrs | 1472544 | n.699C>A | non_coding_transcript_exon_variant | 0.88 |
rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.88 |
rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.93 |
rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.92 |
rrs | 1472579 | n.734G>T | non_coding_transcript_exon_variant | 0.92 |
rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.92 |
rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.91 |
rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.91 |
rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.22 |
rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.94 |
rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.91 |
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.91 |
rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.93 |
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.83 |
rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.83 |
rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.78 |
rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.78 |
rrs | 1472755 | n.910G>A | non_coding_transcript_exon_variant | 0.1 |
rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.74 |
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.1 |
rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.74 |
rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.69 |
rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.47 |
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.55 |
rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.53 |
rrs | 1473093 | n.1248C>T | non_coding_transcript_exon_variant | 0.44 |
rrs | 1473121 | n.1276T>C | non_coding_transcript_exon_variant | 0.36 |
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.41 |
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.4 |
rrs | 1473177 | n.1332G>A | non_coding_transcript_exon_variant | 0.24 |
rrs | 1473192 | n.1347A>G | non_coding_transcript_exon_variant | 0.27 |
rrs | 1473199 | n.1356delA | non_coding_transcript_exon_variant | 0.25 |
rrs | 1473205 | n.1360T>C | non_coding_transcript_exon_variant | 0.25 |
rrl | 1476229 | n.2572C>T | non_coding_transcript_exon_variant | 0.3 |
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.26 |
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.27 |
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.25 |
rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.31 |
rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.36 |
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.52 |
rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.46 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
Rv1979c | 2223128 | p.Lys13Gln | missense_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embA | 4244131 | p.Thr300Met | missense_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
whiB6 | 4338630 | c.-109C>A | upstream_gene_variant | 1.0 |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 |