TB-Profiler result

Run: ERR4814785

Summary

Run ID: ERR4814785

Sample name:

Date: 01-04-2023 13:29:20

Number of reads: 966900

Percentage reads mapped: 99.7

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472355 n.510C>T non_coding_transcript_exon_variant 1.0
rpsA 1834801 c.1260G>A synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155375 p.Val246Ala missense_variant 0.1
katG 2155746 c.366C>T synonymous_variant 0.14
PPE35 2170189 p.Glu142Gln missense_variant 0.1
PPE35 2170190 c.423G>A synonymous_variant 0.1
kasA 2518001 c.-114C>T upstream_gene_variant 0.11
Rv3236c 3611969 p.Ala383Val missense_variant 0.14
fbiA 3641144 p.Ala201Val missense_variant 0.1
fbiB 3641900 c.366G>A synonymous_variant 0.1
clpC1 4038851 c.1854G>A synonymous_variant 0.11
embC 4239720 c.-143G>C upstream_gene_variant 0.18
embC 4240408 c.546A>G synonymous_variant 0.11
embC 4241739 p.Val626Gly missense_variant 0.14
aftB 4268846 c.-10G>T upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0