TB-Profiler result

Run: ERR4815161
Summary

Run ID: ERR4815161

Sample name:

Date: 01-04-2023 13:42:34

Number of reads: 1327352

Percentage reads mapped: 99.74

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 620748 c.858T>G synonymous_variant 0.24
fbiC 1303016 p.Val29Gly missense_variant 0.21
fbiC 1304225 p.Gly432Asp missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472195 n.350G>T non_coding_transcript_exon_variant 0.17
rrs 1472563 n.718G>A non_coding_transcript_exon_variant 0.11
rrl 1474784 n.1127C>G non_coding_transcript_exon_variant 0.15
PPE35 2169639 p.Gly325Val missense_variant 0.14
PPE35 2170135 p.Ala160Ser missense_variant 0.17
Rv3083 3448803 p.Tyr100* stop_gained 0.11
fbiB 3642227 c.693A>G synonymous_variant 0.11
fbiB 3642229 p.Leu232Gln missense_variant 0.11
fbiB 3642232 p.Leu233Gln missense_variant 0.11
fbiB 3642234 p.Arg234Leu missense_variant 0.11
clpC1 4038162 p.Arg848Leu missense_variant 0.11