TB-Profiler result

Run: ERR4815365
Summary

Run ID: ERR4815365

Sample name:

Date: 01-04-2023 13:49:31

Number of reads: 2375010

Percentage reads mapped: 99.63

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.98
mshA 576586 c.1239G>A synonymous_variant 0.97
rpoB 759615 c.-192A>C upstream_gene_variant 0.19
rpoC 763555 c.186C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 779601 c.-696A>C upstream_gene_variant 1.0
rpsL 781383 c.-177G>C upstream_gene_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472592 n.747C>A non_coding_transcript_exon_variant 0.13
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474200 n.543A>G non_coding_transcript_exon_variant 0.22
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.4
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.4
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.4
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.4
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.4
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.5
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.5
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.33
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.67
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.4
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.4
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.4
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.4
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 0.98
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746970 p.Ala210Val missense_variant 0.99
Rv3083 3448322 c.-182G>A upstream_gene_variant 0.98
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4326169 c.1305C>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0