TB-Profiler result

Run: ERR4815434
Summary

Run ID: ERR4815434

Sample name:

Date: 01-04-2023 13:51:42

Number of reads: 202393

Percentage reads mapped: 98.91

Strain: lineage4.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
rpoB 759920 c.114G>A synonymous_variant 0.33
rpoC 764140 c.771C>T synonymous_variant 0.4
rpoC 764411 p.Ile348Val missense_variant 0.33
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781551 c.-9A>G upstream_gene_variant 0.29
atpE 1460931 c.-114_-113insT upstream_gene_variant 0.18
atpE 1461063 p.Ala7Thr missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674609 c.408G>A synonymous_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102299 p.Met248Ile missense_variant 0.14
Rv1979c 2222474 p.Ala231Thr missense_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519064 p.Ile317Asn missense_variant 0.67
ribD 2987528 c.690A>G synonymous_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4240388 p.Asn176Asp missense_variant 1.0
embC 4240999 p.Trp379Cys missense_variant 0.5
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247771 p.Glu420Lys missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0