TB-Profiler result

Run: ERR4815632
Summary

Run ID: ERR4815632

Sample name:

Date: 01-04-2023 13:58:33

Number of reads: 870275

Percentage reads mapped: 99.94

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8485 p.Val395Ala missense_variant 0.11
mshA 576457 c.1110G>A synonymous_variant 0.17
rpoB 759620 c.-187A>C upstream_gene_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.67
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.67
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.33
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.29
rpsA 1834065 p.Glu175Val missense_variant 0.11
PPE35 2170096 c.517C>A synonymous_variant 0.1
folC 2746764 p.Leu279Met missense_variant 0.11
Rv2752c 3064884 c.1308C>G synonymous_variant 0.1
thyX 3067495 p.Glu151* stop_gained 0.11
ddn 3986652 c.-192_-191insG upstream_gene_variant 0.12
embC 4239968 p.Ala36Ser missense_variant 0.12
embC 4240090 c.228C>A synonymous_variant 0.13
embA 4243781 c.549C>T synonymous_variant 0.11
embA 4245942 p.Arg904Cys missense_variant 0.11
embB 4245965 c.-549A>T upstream_gene_variant 0.12
aftB 4269369 c.-533G>A upstream_gene_variant 0.12