TB-Profiler result

Run: ERR4815742

Summary

Run ID: ERR4815742

Sample name:

Date: 01-04-2023 14:02:06

Number of reads: 972418

Percentage reads mapped: 99.93

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 763091 c.-279G>A upstream_gene_variant 0.13
rpoC 763148 c.-222G>A upstream_gene_variant 0.12
rpoC 766682 p.Val1105Ile missense_variant 0.11
embR 1417212 p.Arg46Cys missense_variant 0.14
atpE 1461128 p.Asp28Glu missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471726 n.-120A>G upstream_gene_variant 0.12
inhA 1674572 p.Ala124Val missense_variant 0.12
tlyA 1918687 p.Ala250Ser missense_variant 0.11
tlyA 1918739 p.Gly267Asp missense_variant 0.13
Rv1979c 2222226 c.939C>T synonymous_variant 0.11
ribD 2986812 c.-27C>T upstream_gene_variant 0.12
ribD 2986866 p.Ala10Ser missense_variant 0.12
Rv2752c 3065609 p.Gly195Ser missense_variant 0.15
Rv3083 3448919 p.Cys139Phe missense_variant 0.12
alr 3840209 p.Glu404Asp missense_variant 0.11
alr 3841184 c.237A>G synonymous_variant 0.13
ddn 3986880 c.38delT frameshift_variant 1.0
clpC1 4040058 p.Gly216Asp missense_variant 0.14
embC 4241633 p.Gly591Arg missense_variant 0.18
embB 4247267 p.Leu252Ile missense_variant 0.1
embB 4247650 c.1137C>A synonymous_variant 0.13
embB 4248839 p.Pro776Ser missense_variant 0.12
embB 4249419 p.Pro969Leu missense_variant 0.11
aftB 4267165 p.Trp558Arg missense_variant 0.13
ethR 4327138 c.-411C>T upstream_gene_variant 0.11