TB-Profiler result

Run: ERR4815825

Summary

Run ID: ERR4815825

Sample name:

Date: 01-04-2023 14:05:00

Number of reads: 196348

Percentage reads mapped: 99.45

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575891 p.Ala182Thr missense_variant 1.0
mshA 576581 p.Pro412Ser missense_variant 0.14
rpoB 763240 p.Glu1145Gly missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170761 c.-149G>A upstream_gene_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747772 c.-174C>G upstream_gene_variant 0.33
ribD 2987160 p.Ala108Pro missense_variant 0.33
ribD 2987265 p.Leu143Phe missense_variant 0.22
Rv2752c 3065834 p.Arg120Ser missense_variant 0.33
embC 4241662 c.1800G>A synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247595 p.Cys361Ser missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0