TB-Profiler result

Run: ERR4815889
Summary

Run ID: ERR4815889

Sample name:

Date: 01-04-2023 14:07:14

Number of reads: 982069

Percentage reads mapped: 99.77

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 620064 c.174C>T synonymous_variant 0.14
rpoC 764123 p.Phe252Val missense_variant 0.12
fbiC 1303016 p.Val29Gly missense_variant 0.25
atpE 1460910 c.-135G>T upstream_gene_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.4
inhA 1674911 p.Pro237Arg missense_variant 0.1
katG 2155209 p.Lys301Asn missense_variant 0.1
katG 2155250 p.Pro288Ser missense_variant 0.12
PPE35 2167944 p.Ser890* stop_gained 0.12
pncA 2289407 c.-166G>A upstream_gene_variant 0.13
ahpC 2726341 p.Val50Gly missense_variant 0.22
Rv2752c 3065478 c.714C>T synonymous_variant 0.14
Rv3083 3448638 p.Trp45Cys missense_variant 0.14
Rv3236c 3613234 c.-118G>T upstream_gene_variant 0.13
fbiA 3640483 c.-60G>A upstream_gene_variant 0.11
clpC1 4039716 p.Lys330Met missense_variant 0.12
embB 4247066 p.Ile185Val missense_variant 0.19