TB-Profiler result

Run: ERR4816080
Summary

Run ID: ERR4816080

Sample name:

Date: 01-04-2023 14:13:38

Number of reads: 263114

Percentage reads mapped: 99.44

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 766133 p.Ala922Thr missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777152 p.Met443Ile missense_variant 0.75
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.67
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.67
rrl 1475611 n.1954T>C non_coding_transcript_exon_variant 0.18
ndh 2102185 c.858C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726088 c.-105G>A upstream_gene_variant 0.2
thyA 3074527 c.-56C>T upstream_gene_variant 0.83
fbiB 3642427 p.Val298Ala missense_variant 0.33
ddn 3987034 p.Leu64Pro missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267149 p.Glu563Gly missense_variant 1.0
aftB 4267155 p.Gln561Arg missense_variant 1.0
ubiA 4269831 c.3G>T start_lost 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0