TB-Profiler result

Run: ERR4816082
Summary

Run ID: ERR4816082

Sample name:

Date: 01-04-2023 14:13:43

Number of reads: 444216

Percentage reads mapped: 98.87

Strain: lineage4.1.1.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1.2 Euro-American (X-type) X1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6889 c.-413G>A upstream_gene_variant 0.4
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8182 p.Gly294Asp missense_variant 0.67
gyrA 8303 c.1002C>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575782 c.435G>C synonymous_variant 0.1
mshA 575800 c.453G>C synonymous_variant 0.1
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778313 c.-677G>A upstream_gene_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460936 c.-109T>C upstream_gene_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 1.0
rpsA 1833758 p.Asp73Asn missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168681 p.Phe644Leu missense_variant 0.75
Rv1979c 2221724 p.Arg481Ser missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518454 p.Thr114Ala missense_variant 0.44
kasA 2518697 p.Cys195Arg missense_variant 0.1
Rv2752c 3065377 c.813_814delCG frameshift_variant 0.22
Rv2752c 3065881 p.Gly104Asp missense_variant 0.22
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339761 c.644G>T stop_lost&splice_region_variant 0.15
Rv3083 3449787 c.1284C>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568434 c.243_245delTCC disruptive_inframe_deletion 0.1
whiB7 3568735 c.-56G>A upstream_gene_variant 0.2
fbiB 3641562 p.Ser10Pro missense_variant 0.11
fbiB 3642627 p.Arg365Ser missense_variant 0.25
rpoA 3877865 c.643C>T synonymous_variant 0.17
ddn 3986760 c.-84G>T upstream_gene_variant 0.22
ddn 3986820 c.-24C>A upstream_gene_variant 1.0
embC 4240608 c.747delC frameshift_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243833 p.Ala201Thr missense_variant 1.0
embB 4246930 p.Gln139His missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408436 c.-234C>A upstream_gene_variant 0.25