TB-Profiler result

Run: ERR4816391
Summary

Run ID: ERR4816391

Sample name:

Date: 01-04-2023 14:24:09

Number of reads: 96332

Percentage reads mapped: 98.28

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.89
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7829 c.531delG frameshift_variant 1.0
mmpL5 776888 c.1593C>A synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302768 c.-163G>A upstream_gene_variant 0.67
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674879 c.678T>C synonymous_variant 0.5
ndh 2102734 c.308delT frameshift_variant 0.4
PPE35 2169884 c.729T>C synonymous_variant 0.5
PPE35 2170559 c.54G>C synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747259 p.Pro114Ser missense_variant 0.67
fprA 3474609 c.603T>C synonymous_variant 0.67
alr 3840806 p.Asp205Glu missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244705 c.1473G>C synonymous_variant 0.67
embA 4245787 p.Ala852Asp missense_variant 0.5
embA 4246171 p.Asp980Val missense_variant 0.5
embB 4248817 c.2304C>T synonymous_variant 0.5
embB 4249449 p.Gly979Asp missense_variant 1.0
ethR 4326868 c.-681G>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407578 p.Lys209Glu missense_variant 0.33