TB-Profiler result

Run: ERR4816440
Summary

Run ID: ERR4816440

Sample name:

Date: 01-04-2023 14:25:49

Number of reads: 289280

Percentage reads mapped: 98.89

Strain: lineage4.1.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1.2 Euro-American (X-type) X1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491588 p.Glu269Val missense_variant 0.4
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302814 c.-117C>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156536 c.-425C>A upstream_gene_variant 0.22
PPE35 2167675 c.2938C>T synonymous_variant 0.33
Rv1979c 2222708 p.Leu153Ile missense_variant 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290071 c.-830A>G upstream_gene_variant 0.29
kasA 2519143 c.1029G>T synonymous_variant 0.18
folC 2746966 c.633G>T synonymous_variant 0.18
thyX 3067784 c.162C>A synonymous_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449787 c.1284C>T synonymous_variant 1.0
clpC1 4038826 p.Ile627Val missense_variant 0.5
clpC1 4039956 p.Leu250Pro missense_variant 0.22
embC 4241572 c.1710C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243833 p.Ala201Thr missense_variant 1.0
embA 4246373 c.3145delG frameshift_variant 0.29
embB 4249408 c.2895G>A synonymous_variant 1.0
ubiA 4269358 c.475delA frameshift_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0