TB-Profiler result

Run: ERR4816501
Summary

Run ID: ERR4816501

Sample name:

Date: 01-04-2023 14:27:50

Number of reads: 133252

Percentage reads mapped: 97.16

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7222 p.Ser661Arg missense_variant 0.5
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9078 p.Gly593Trp missense_variant 0.18
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9705 p.Arg802Trp missense_variant 0.29
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 620746 p.Gly286Cys missense_variant 0.67
rpoB 759620 c.-187A>C upstream_gene_variant 0.29
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 760015 p.Glu70Val missense_variant 1.0
rpoB 761357 c.1551G>T synonymous_variant 0.67
rpoB 761873 c.2067A>G synonymous_variant 0.33
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 762617 c.-753C>A upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763525 c.156C>T synonymous_variant 0.4
rpoC 764747 p.Leu460Met missense_variant 0.33
rpoC 765450 p.Ala694Val missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 778333 p.Val50Leu missense_variant 0.18
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801253 p.Gly149Ser missense_variant 0.5
Rv1258c 1406683 p.Trp220Arg missense_variant 0.29
embR 1416790 c.558G>T synonymous_variant 0.2
embR 1416795 p.Gly185Trp missense_variant 0.2
embR 1416926 p.Ala141Glu missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674872 p.Gln224Arg missense_variant 0.4
tlyA 1917927 c.-13G>T upstream_gene_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726341 p.Val50Gly missense_variant 0.5
ribD 2987351 c.513C>T synonymous_variant 0.4
ribD 2987469 c.631C>T synonymous_variant 0.33
Rv2752c 3064893 c.1299C>T synonymous_variant 0.4
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568421 p.Arg87Cys missense_variant 0.4
Rv3236c 3612429 p.Ala230Ser missense_variant 0.25
Rv3236c 3612861 c.256C>T synonymous_variant 0.67
fbiB 3642212 c.678C>A synonymous_variant 0.67
fbiB 3642776 c.1242G>A synonymous_variant 1.0
alr 3841473 c.-53G>A upstream_gene_variant 1.0
clpC1 4038319 p.Pro796Ser missense_variant 0.4
embC 4240578 p.Ala239Val missense_variant 0.5
embC 4242075 p.Arg738Gln missense_variant 1.0
embB 4247184 p.Gly224Glu missense_variant 0.25
embB 4247242 p.Asp243Glu missense_variant 0.33
whiB6 4338208 p.Pro105Gln missense_variant 0.5
whiB6 4338497 p.Ala9Ser missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0