TB-Profiler result

Run: ERR4816524
Summary

Run ID: ERR4816524

Sample name:

Date: 01-04-2023 14:28:34

Number of reads: 134842

Percentage reads mapped: 88.26

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 759810 p.Ala2Thr missense_variant 0.5
rpoB 762300 p.Lys832* stop_gained 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289547 c.-307delC upstream_gene_variant 1.0
kasA 2518387 c.273C>A synonymous_variant 0.67
kasA 2518896 p.Pro261Leu missense_variant 0.33
ahpC 2726210 c.18T>C synonymous_variant 1.0
ribD 2987205 c.369delC frameshift_variant 0.5
thyX 3067367 c.579G>C synonymous_variant 0.33
thyX 3067373 c.573C>G synonymous_variant 0.29
thyX 3067376 c.570G>A synonymous_variant 0.25
thyX 3067391 c.555G>C synonymous_variant 0.29
thyX 3067394 c.552G>C synonymous_variant 0.29
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641447 p.Thr302Met missense_variant 1.0
fbiB 3641565 p.Thr11Ser missense_variant 0.5
alr 3840555 p.Ala289Val missense_variant 0.33
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243623 p.Ile131Val missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
ubiA 4269637 c.196delG frameshift_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407681 p.His174Gln missense_variant 1.0