TB-Profiler result

Run: ERR4816703
Summary

Run ID: ERR4816703

Sample name:

Date: 01-04-2023 14:34:55

Number of reads: 2031955

Percentage reads mapped: 98.68

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
ccsA 620566 p.Asp226Asn missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.18
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.27
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.27
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.2
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.18
rrs 1472682 n.837T>G non_coding_transcript_exon_variant 0.27
rrs 1472683 n.838T>G non_coding_transcript_exon_variant 0.18
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.27
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.18
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.27
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.27
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.3
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.2
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.5
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.5
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.5
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.5
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.5
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.5
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.5
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.67
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.67
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.75
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.75
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.6
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.6
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.6
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.6
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.6
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.6
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.4
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.4
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.4
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.4
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.4
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.5
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.15
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.23
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.15
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.18
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.27
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.18
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.11
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.12
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.12
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.12
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.12
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.14
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.14
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.14
rpsA 1833424 c.-118C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714308 p.Pro342Leu missense_variant 1.0
thyA 3074592 c.-121G>A upstream_gene_variant 1.0
ald 3087510 p.Arg231Ser missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248548 p.Ala679Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0