TB-Profiler result

Run: ERR4816734
Summary

Run ID: ERR4816734

Sample name:

Date: 01-04-2023 14:35:53

Number of reads: 5698

Percentage reads mapped: 8.32

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6673 c.-629A>C upstream_gene_variant 1.0
gyrA 6676 c.-626T>G upstream_gene_variant 1.0
gyrA 6700 c.-602T>C upstream_gene_variant 1.0
gyrA 6703 c.-599G>C upstream_gene_variant 1.0
gyrA 6706 c.-596G>A upstream_gene_variant 1.0
gyrA 6709 c.-593A>G upstream_gene_variant 1.0
gyrA 6712 c.-590G>C upstream_gene_variant 1.0
gyrA 6727 c.-575G>T upstream_gene_variant 1.0
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 1.0
gyrA 6739 c.-563C>T upstream_gene_variant 1.0
gyrA 6745 c.-557T>C upstream_gene_variant 1.0
gyrA 6754 c.-548C>T upstream_gene_variant 1.0
gyrA 6763 c.-539G>C upstream_gene_variant 1.0
rpoB 762026 c.2220G>C synonymous_variant 1.0
rpoB 762053 c.2247T>C synonymous_variant 1.0
rpoB 762057 p.Ile751Val missense_variant 1.0
rpoB 762062 c.2256T>C synonymous_variant 0.67
rpoB 762065 c.2259T>C synonymous_variant 1.0
rpoB 762086 c.2280G>C synonymous_variant 1.0
rpoC 764308 c.939G>C synonymous_variant 1.0
rpoC 764311 c.942C>G synonymous_variant 1.0
rpoC 764344 c.975C>T synonymous_variant 1.0
rpoC 764359 c.990C>G synonymous_variant 1.0
rpoC 764371 c.1002G>C synonymous_variant 1.0
rpoC 764377 c.1008C>G synonymous_variant 1.0
rpoC 764380 c.1011G>C synonymous_variant 1.0
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0
rpoC 767158 c.3789T>C synonymous_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.5
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.67
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.5
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.67
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.5
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.83
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.83
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.4
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.33
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 1.0
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472954 n.1110delC non_coding_transcript_exon_variant 1.0
rrs 1472958 n.1113_1114insC non_coding_transcript_exon_variant 1.0
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 1.0
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 1.0
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474784 n.1127C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.67
rrl 1475514 n.1857G>A non_coding_transcript_exon_variant 0.67
rrl 1475525 n.1868G>A non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.67
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0
rrl 1475542 n.1885A>G non_coding_transcript_exon_variant 1.0
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.33
rrl 1476363 n.2706A>G non_coding_transcript_exon_variant 0.29
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 0.29
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.29
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.29
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.29
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.5
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.75
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.33
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.67
aftB 4268614 p.Gly75Arg missense_variant 1.0
ubiA 4269689 p.Val49Ile missense_variant 1.0