TB-Profiler result

Run: ERR4816991
Summary

Run ID: ERR4816991

Sample name:

Date: 01-04-2023 14:44:40

Number of reads: 6257

Percentage reads mapped: 1.91

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762923 c.-447C>G upstream_gene_variant 1.0
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 1.0
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 1.0
rpoB 763075 p.Thr1090Ile missense_variant 1.0
rpoB 763077 p.Val1091Leu missense_variant 1.0
rpoC 763103 c.-267G>C upstream_gene_variant 1.0
rpoC 763507 c.138G>C synonymous_variant 1.0
rpoC 763534 c.165T>C synonymous_variant 1.0
rpoC 763546 c.177A>G synonymous_variant 1.0
rpoC 763573 c.204G>C synonymous_variant 0.67
rpoC 763633 c.264T>C synonymous_variant 0.67
rpoC 763660 c.291T>C synonymous_variant 1.0
rpoC 763669 c.300C>G synonymous_variant 1.0
rpoC 764338 p.Glu323Asp missense_variant 1.0
rpoC 764353 c.984G>C synonymous_variant 1.0
rpoC 764359 c.990C>G synonymous_variant 1.0
rpoC 764371 c.1002G>C synonymous_variant 1.0
rpoC 764377 c.1008C>G synonymous_variant 1.0
rpoC 764380 c.1011G>C synonymous_variant 1.0
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0
rpsL 781740 p.Val61Ile missense_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 1.0
rpsL 781754 c.195G>C synonymous_variant 1.0
rpsL 781760 c.201T>C synonymous_variant 1.0
rpsL 781768 p.Glu70Val missense_variant 1.0
rpsL 781802 c.243G>C synonymous_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.83
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.33
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.4
rrs 1472213 n.368G>A non_coding_transcript_exon_variant 0.4
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.8
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.8
rrs 1472236 n.391C>T non_coding_transcript_exon_variant 0.4
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.6
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 1.0
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.5
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.4
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.4
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.6
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.86
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.86
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.33
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.5
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.67
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.67
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 1.0
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.75
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.75
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.67
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 1.0
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 1.0
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 1.0
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 1.0
rrs 1473097 n.1252G>C non_coding_transcript_exon_variant 1.0
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.67
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 1.0
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 1.0
rrl 1474234 n.577G>T non_coding_transcript_exon_variant 0.67
rrl 1474237 n.580A>C non_coding_transcript_exon_variant 0.67
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.67
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 1.0
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 1.0
clpC1 4038575 c.2130C>G synonymous_variant 1.0
clpC1 4038596 c.2109A>G synonymous_variant 1.0
clpC1 4038621 p.Gln695Ser missense_variant 1.0
clpC1 4038623 c.2082A>G synonymous_variant 1.0