TB-Profiler result

Run: ERR4817154
Summary

Run ID: ERR4817154

Sample name:

Date: 01-04-2023 14:49:55

Number of reads: 95861

Percentage reads mapped: 96.13

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1.2 Euro-American T;H None 0.12
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 760763 c.957C>A synonymous_variant 0.5
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 767202 p.Ala1278Asp missense_variant 0.5
embR 1417140 p.Ala70Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154383 p.Glu577Gln missense_variant 0.4
PPE35 2168750 p.Ser621Arg missense_variant 0.67
Rv3083 3448894 p.Tyr131Asp missense_variant 1.0
Rv3083 3449642 p.Asn380Ser missense_variant 1.0
alr 3841548 c.-128A>G upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243889 c.657G>A synonymous_variant 0.67
embA 4246483 p.Trp1084* stop_gained 1.0
embB 4248707 p.Thr732Ala missense_variant 0.67
embB 4249226 p.Pro905Ser missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0