TB-Profiler result

Run: ERR4817253
Summary

Run ID: ERR4817253

Sample name:

Date: 01-04-2023 14:53:21

Number of reads: 294682

Percentage reads mapped: 99.66

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620302 c.415delG frameshift_variant 0.4
rpoB 760134 p.Lys110Glu missense_variant 0.29
rpoB 761864 c.2058G>T synonymous_variant 0.25
rpoB 762543 c.2740delC frameshift_variant 0.33
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765250 c.1881G>A synonymous_variant 0.33
rpoC 766659 p.Arg1097Gln missense_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407018 p.Val108Glu missense_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102021 p.Lys341Arg missense_variant 0.25
ndh 2102510 p.Ala178Val missense_variant 0.33
katG 2156173 c.-62C>A upstream_gene_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860161 c.258G>A synonymous_variant 0.18
ribD 2987185 p.Gln116Arg missense_variant 0.18
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339167 p.Lys17Arg missense_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
ddn 3987173 c.330C>T synonymous_variant 0.33
clpC1 4038287 c.2418C>T synonymous_variant 1.0
panD 4044131 p.Asn51Asp missense_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ubiA 4269864 c.-32delG upstream_gene_variant 0.25
ethA 4326041 p.Leu478Pro missense_variant 0.4
ethR 4327693 p.Asp49Asn missense_variant 0.25
whiB6 4338594 c.-75delG upstream_gene_variant 0.71
gid 4408156 p.Leu16Arg missense_variant 1.0