TB-Profiler result

Run: ERR4817263
Summary

Run ID: ERR4817263

Sample name:

Date: 01-04-2023 14:53:35

Number of reads: 29595

Percentage reads mapped: 77.8

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6775 c.-527G>T upstream_gene_variant 1.0
gyrA 6796 c.-506C>T upstream_gene_variant 1.0
gyrB 6798 p.Gly520Ala missense_variant 1.0
gyrA 6808 c.-494C>G upstream_gene_variant 1.0
gyrA 6811 c.-491C>T upstream_gene_variant 1.0
gyrA 6824 c.-478C>T upstream_gene_variant 1.0
gyrA 6841 c.-461T>C upstream_gene_variant 1.0
gyrA 6856 c.-446T>C upstream_gene_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8704 p.Ile468Thr missense_variant 1.0
mshA 575734 c.387T>G synonymous_variant 1.0
mshA 575737 c.390T>C synonymous_variant 1.0
mshA 575740 c.393G>A synonymous_variant 1.0
mshA 575744 p.Ala133Thr missense_variant 1.0
mshA 575756 c.409C>T synonymous_variant 1.0
mshA 575779 c.432A>G synonymous_variant 1.0
mshA 575785 c.438T>C synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781832 c.273T>C synonymous_variant 1.0
rpsL 781859 c.300T>C synonymous_variant 1.0
rpsL 781868 c.309T>C synonymous_variant 1.0
rpsL 781871 c.312G>C synonymous_variant 1.0
rpsL 781877 c.318T>A synonymous_variant 1.0
rpsL 781892 c.333A>G synonymous_variant 1.0
rpsL 781898 c.339A>T synonymous_variant 1.0
rpsL 781907 c.348T>C synonymous_variant 1.0
rpsL 781916 c.357T>C synonymous_variant 0.67
fbiC 1304667 c.1737G>C synonymous_variant 0.5
fbiC 1304671 p.Val581Thr missense_variant 0.5
fbiC 1304675 p.Gly582Asp missense_variant 0.5
fbiC 1304682 c.1752C>G synonymous_variant 0.5
fbiC 1304691 c.1761G>C synonymous_variant 0.5
fbiC 1304694 c.1764A>C synonymous_variant 0.5
fbiC 1304703 c.1773C>G synonymous_variant 0.5
embR 1416683 p.Ser222Tyr missense_variant 0.5
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 1.0
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 1.0
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 1.0
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289649 c.-408G>A upstream_gene_variant 0.33
Rv2752c 3064835 c.1356delG frameshift_variant 1.0
Rv3083 3449314 c.814delG frameshift_variant 1.0
embA 4244670 p.Ala480Ser missense_variant 1.0