TB-Profiler result

Run: ERR4817329

Summary

Run ID: ERR4817329

Sample name:

Date: 01-04-2023 14:55:50

Number of reads: 119731

Percentage reads mapped: 95.81

Strain:

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8452 p.Ala384Val missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
embR 1417019 p.Cys110Tyr missense_variant 1.0
embR 1417395 c.-48G>T upstream_gene_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674279 c.78A>T synonymous_variant 0.5
rpsA 1834348 c.807T>C synonymous_variant 0.67
rpsA 1834366 c.825A>G synonymous_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167983 p.Gly877Asp missense_variant 1.0
PPE35 2170785 c.-173T>C upstream_gene_variant 1.0
eis 2715016 p.Arg106His missense_variant 1.0
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ribD 2987261 c.423G>A synonymous_variant 1.0
Rv2752c 3065419 p.Arg258Leu missense_variant 1.0
fbiD 3339304 c.192delC frameshift_variant 0.4
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243848 p.Val206Met missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4249118 p.Asp869Asn missense_variant 0.33
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4327842 c.-369G>A upstream_gene_variant 0.67
gid 4407588 c.615A>G synonymous_variant 1.0