TB-Profiler result

Run: ERR4817349
Summary

Run ID: ERR4817349

Sample name:

Date: 01-04-2023 14:56:48

Number of reads: 2230692

Percentage reads mapped: 97.89

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.12 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.14 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.25
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.14
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.16
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.22
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.22
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.18
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.17
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.27
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.21
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.21
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.12
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.27
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.22
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.17
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.13
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.21
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.14
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.25
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.15
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.14
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.2
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.29
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.14
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.13
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.17
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.17
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.18
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.19
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.24
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.24
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.29
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.29
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.25
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.22
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.22
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.26
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.29
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.21
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.18
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.19
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.2
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.21
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.2
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.24
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.24
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.2
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.27
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.23
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.17
rrl 1475696 n.2039T>G non_coding_transcript_exon_variant 0.29
rrl 1475703 n.2046A>C non_coding_transcript_exon_variant 0.29
rrl 1475706 n.2049A>C non_coding_transcript_exon_variant 0.33
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.33
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.33
rrl 1475735 n.2078T>C non_coding_transcript_exon_variant 0.25
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.29
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.33
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.33
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.33
rrl 1475783 n.2126T>C non_coding_transcript_exon_variant 0.33
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.33
rrl 1476197 n.2540T>C non_coding_transcript_exon_variant 0.33
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103168 c.-126G>A upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726691 c.502delC frameshift_variant 1.0
panD 4043925 c.357C>T synonymous_variant 1.0
aftB 4268019 p.Ser273Leu missense_variant 1.0
ethR 4327670 p.Pro41Arg missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0