TB-Profiler result

Run: ERR4817384
Summary

Run ID: ERR4817384

Sample name:

Date: 01-04-2023 14:57:51

Number of reads: 1233310

Percentage reads mapped: 99.14

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5248 c.9C>T synonymous_variant 1.0
gyrB 5805 p.Thr189Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.96
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 0.98
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.17
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.15
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.18
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.25
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.25
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.25
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.2
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.18
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.3
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.4
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.5
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.5
rrs 1472559 n.714T>A non_coding_transcript_exon_variant 0.67
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.67
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.67
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.67
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.67
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 1.0
rrs 1472592 n.747C>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 1.0
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 1.0
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.67
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.18
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.15
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.17
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.27
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.36
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.33
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.33
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.2
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.2
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.2
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.2
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.2
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.2
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.2
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.2
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.2
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.15
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.15
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.15
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.33
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.33
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.22
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715568 c.-236G>T upstream_gene_variant 0.12
thyA 3074645 c.-174T>G upstream_gene_variant 0.21
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338238 p.Leu95Arg missense_variant 0.11
whiB6 4338241 c.280delC frameshift_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 0.89