TB-Profiler result

Run: ERR4817586
Summary

Run ID: ERR4817586

Sample name:

Date: 01-04-2023 15:04:43

Number of reads: 80420

Percentage reads mapped: 93.26

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.88
lineage4.9 Euro-American (H37Rv-like) T1 None 0.89
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.08
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416480 p.Ala290Ser missense_variant 1.0
rrl 1474732 n.1075A>G non_coding_transcript_exon_variant 0.5
PPE35 2168723 c.1890A>T synonymous_variant 0.67
pepQ 2860572 c.-154G>A upstream_gene_variant 1.0
thyA 3073860 c.612C>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449279 p.Arg259Gln missense_variant 0.5
Rv3236c 3612694 c.423T>C synonymous_variant 0.4
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0