TB-Profiler result

Run: ERR4818159
Summary

Run ID: ERR4818159

Sample name:

Date: 01-04-2023 15:24:01

Number of reads: 80133

Percentage reads mapped: 86.13

Strain: lineage4.9;lineage4.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.06
lineage4.9 Euro-American (H37Rv-like) T1 None 0.93
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
ccsA 620010 c.120C>A synonymous_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777914 c.567G>A synonymous_variant 0.67
mmpS5 779496 c.-591G>T upstream_gene_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.5
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.4
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.4
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.5
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
ribD 2986906 p.Leu23Pro missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
clpC1 4038808 p.Glu633Gln missense_variant 1.0
clpC1 4040552 c.153G>C synonymous_variant 1.0
embB 4249328 p.Met939Val missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0