TB-Profiler result

Run: ERR4818363
Summary

Run ID: ERR4818363

Sample name:

Date: 01-04-2023 15:31:00

Number of reads: 727066

Percentage reads mapped: 99.9

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5941 p.Ser234Arg missense_variant 0.11
ccsA 620748 c.858T>G synonymous_variant 0.27
rpoB 761457 p.Pro551Ser missense_variant 0.12
mmpR5 778448 c.-542G>A upstream_gene_variant 0.11
mmpS5 778662 p.Asp82His missense_variant 0.15
fbiC 1303215 c.285C>A synonymous_variant 0.12
Rv1258c 1407252 p.Phe30Ser missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474615 n.958A>T non_coding_transcript_exon_variant 0.5
fabG1 1673776 p.Leu113Phe missense_variant 0.14
rpsA 1833442 c.-100G>A upstream_gene_variant 0.14
PPE35 2169326 p.Asn429Lys missense_variant 0.13
Rv1979c 2222144 p.Ser341Thr missense_variant 0.17
kasA 2518995 p.Ser294Leu missense_variant 0.11
kasA 2519070 p.Asp319Val missense_variant 0.1
folC 2746536 p.Asn355Tyr missense_variant 0.11
pepQ 2859876 c.543C>T synonymous_variant 0.15
thyA 3074648 c.-177T>G upstream_gene_variant 0.33
fbiA 3640988 p.Arg149His missense_variant 0.13
embC 4241655 p.Gly598Glu missense_variant 0.13
ethA 4326228 p.Thr416Ser missense_variant 0.11