TB-Profiler result

Run: ERR4818463

Summary

Run ID: ERR4818463

Sample name:

Date: 01-04-2023 15:34:12

Number of reads: 1092738

Percentage reads mapped: 99.96

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760959 p.Val385Phe missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473064 n.1219A>G non_coding_transcript_exon_variant 0.22
rrl 1476028 n.2371A>G non_coding_transcript_exon_variant 0.5
PPE35 2170066 p.Ala183Thr missense_variant 0.12
ribD 2987153 c.315C>T synonymous_variant 0.1
embA 4244569 p.Arg446Leu missense_variant 0.11
aftB 4268639 c.198G>A synonymous_variant 0.11